IL13 receptor alpha 1 (IL13RA1) (Extracell. Dom.) Mouse Monoclonal Antibody [Clone ID: GM1E7]

CAT#: DM1227

IL13 receptor alpha 1 (IL13RA1) (Extracell. Dom.) mouse monoclonal antibody, clone GM1E7, Purified



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CNY 5,660.00


货期*
5周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name GM1E7
Applications ELISA, FC, IF
Recommend Dilution Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
Flow cytometry: 1.2 µg/106 cells.
Immunofluorescence: 1 µg/106 cells.
Specific inhibition of IL-13-dependent proliferation of TF-1 cells by GM-1E7 (See Figure.3).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Genetic immunization with cDNA encoding Human IL13-R alpha 1 (extracellular domain).
Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
Specificity Recognizes IL13 Receptor (IL13-R).
Formulation Phosphate buffered saline, pH 7.2 without preservatives
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name interleukin 13 receptor subunit alpha 1
Background Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation
Synonyms Interleukin-13 receptor alpha-1 chain, IL-13R-alpha-1, IL-13RA-1, IL13R, IL13RA, IL13 receptor alpha, CT19
Note SDS-PAGE analysis: The antibody was purified by Protein G Affinity Chromatography from cell culture supernatants and verified by SDS-Page (Figure.4).
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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