CD10 (MME) Mouse Monoclonal Antibody [Clone ID: 56C6]

Specifications

Product Data
Clone Name	56C6
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Embedded Sections: Use 1/20-1/30 dilution in an ABC method. High temperature antigen unmasking is required prior to immunostaining of formalin fixed paraffin embedded tissue sections. Incubation Time: 30 minutes at RT. Positive Control: Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to the external domain of the CD10 glycoprotein
Specificity	This antibody is specific to human CD10 antigen of 100 kD, also known as common acute lymphocytic leukemia antigen (CALLA). Cellular Localization: Cell membrane.
Formulation	State: Supernatant State: Liquid Tissue Culture Supernatant containing Sodium Azide as preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C Avoid repeated freezing and thawing.
Gene Name	membrane metallo-endopeptidase
Database Link	Entrez Gene 4311 Human UniProt ID P08473
Background	CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. The CD10 antigen of 100 kD has been identified on the surface of early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.
Synonyms	MME, EPN, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, CALLA
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.