Pancreatic Polypeptide (PPY) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen and Paraffin Embedded Sections: diluted of 1/25 - 1/50 in an ABC method (30 minutes at room temperature) Recommended Positive Control: Pancreas.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Human Pancreatic Polypeptide conjugated to Keyhole Limpet Hemocyanin.
Specificity	This antibody reacts with Pancreatic Polypeptide. It stains the periphery of islets, exocrine pancreatic parenchyma, and the epithelium of small and medium sized ducts and acinar cells. Cellular Localization: Cytoplasmic.
Formulation	State: Purified State: Liquid Ig fraction containing Sodium Azide as preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	pancreatic polypeptide
Database Link	Entrez Gene 5539 Human UniProt ID P01298
Background	Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
Synonyms	Pancreatic polypeptide, PPY, PNP, Obinepitide
Reference Data

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