alpha 1 Antichymotrypsin (SERPINA3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on frozen sections. Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:25-1:50 in an ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Alpha-1-antichymotrypsin isolated from human serum
Specificity	The antibody is specific against human alpha-1-antichymotrypsin. Cellular Localization: Cytoplasmic.
Formulation	Containing sodium azide as preservative State: Purified State: Liquid Ig fraction
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	serpin family A member 3
Database Link	Entrez Gene 12 Human UniProt ID P01011
Background	Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Synonyms	SERPINA3, AACT, GIG24, GIG25
Note	This antibody shows cross reactivity against wide range of mammalian species.
Reference Data

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