Growth Hormone (GH1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Human GH purified by HPLC.
Specificity	The antibody recognizes Human Growth Hormone.
Formulation	0.01M PBS, pH 7.4 State: Aff - Purified State: Lyophilized purified Ig fraction (98% pure by SDS-PAGE)
Reconstitution Method	Restore with double distilled water to the concentration of 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Prior to and following reconstitution store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	growth hormone 1
Database Link	Entrez Gene 2688 Human UniProt ID P01241
Background	Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expression
Synonyms	Pituitary growth hormone, Growth hormone 1, HGH
Reference Data

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