Chromogranin A (CHGA) Rabbit Monoclonal Antibody [Clone ID: SP12]

Specifications

Product Data
Clone Name	SP12
Applications	IHC
Recommend Dilution	Immunohistochemistry on formalin-fixed paraffin embedded sections: dilute 1:100 in an ABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Pancreas
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein encoding human Chromogranin A
Specificity	This antibody recognizes Chromogranin A. Cellular Localization: Cytoplasmic
Formulation	State: Supernatant State: Liquid tissue culture supernatant containing sodium azide as preservative
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	chromogranin A
Database Link	Entrez Gene 1113 Human UniProt ID P10645
Background	Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Synonyms	Chromogranin-A, CgA, CHGA, SP-I
Reference Data

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