Calcitonin (CALCA) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunofluorescence. Immunohistochemistry on Paraffin and Frozen Sections. Working Dilutions: 1/1000-1/1200 for Immunofluorescence microscopy with overnight incubation at 2-8°C.
Reactivity	Human, Rat
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic Human CGRP (Peninsula)
Specificity	Absorption with 10-100 µg CGRP per ml diluted antiserum abolishes the staining, while while calcitonin does not. Cross-reacts with amylin (IAPP).
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Dissolve the antiserum in 50-100 μl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09 Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.
Synonyms	Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I
Reference Data

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