Cd4 Rat Monoclonal Antibody [Clone ID: YTS191.1]

Specifications

Product Data
Clone Name	YTS191.1
Applications	FC
Recommend Dilution	Flow cytometry: 1/50 - 1/100; use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl. Immunohistochemistry on frozen sections (3).
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody recognises the murine CD4 cell surface antigen, expressed by a subset of T lymphocytes.
Formulation	PBS, pH 7.4, containing 0.09% sodium azide State: Purified State: Liquid IgG fraction
Concentration	lot specific
Purification	Protein G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to one month or at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD4 antigen
Database Link	Entrez Gene 12504 Mouse UniProt ID P06332
Background	CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms	T-cell surface antigen T4/Leu-3
Note	This clone exhibits depleting activity when used in vivo. We recommend the use of SM005LE for this purpose.
Reference Data

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