IGJ (JCHAIN) Mouse Monoclonal Antibody [Clone ID: MC19-9]

Specifications

Product Data
Clone Name	MC19-9
Applications	ELISA, IHC, IP, WB
Recommend Dilution	ELISA (20 µg/ml). Immunoprecipitation (20 µg/ml). Immunohistochemistry on Frozen Sections (1/200). Western blotting (only under Reducing Conditions).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human J Chain.
Specificity	The antibody reacts with Human J chain as tested by ELISA using purified Human Ig fragments as the solid phase target antigen. The antibody does not detect J chain in intact IgM in ELISA assays due to steric hindrance. In Western blotting techniques SM1013P detects J chain in IgM only in reducing conditions.
Formulation	TRIS buffered Saline containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	joining chain of multimeric IgA and IgM
Database Link	Entrez Gene 3512 Human UniProt ID P01591
Background	Immunoglobulin J chain (IGJ) serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also helps to bind these immunoglobulins to secretory components.
Synonyms	IGJ, IGCJ
Reference Data

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