CD3E Mouse Monoclonal Antibody [Clone ID: UCHT1]

CAT#: SM1057APC

CD3E mouse monoclonal antibody, clone UCHT1, APC



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CNY 6,369.00


货期*
4周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name UCHT1
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of neat antibody to label 106 cells or 100 µl whole blood
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.
Spleen cells from immunised BALB/c mice were fused with cells of the P3/NS1/1-Ag4-1 mouse myeloma cell line.
Specificity This antibody recognises a surface protein of peripheral blood T cells of molecular weight 19kD. As a pan T cell marker this antibody is present on more than 95% of circulating human peripheral T cells.
Formulation PBS, pH 7.2
Label: APC
State: Liquid purified IgG fraction
Stabilizer: 1% BSA, 5% Sucrose
Preservative: 0.09% Sodium Azide
Label: Allophycocyanin
Reconstitution Method Restore with distilled water
Purification Affinity Chromatography on Protein G
Conjugation APC
Storage Condition Prior to and following reconstitution store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name CD3e molecule
Background T Cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
Synonyms T3/Leu-4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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