CD3E Mouse Monoclonal Antibody [Clone ID: UCHT1]

CAT#: SM1057LE

CD3E mouse monoclonal antibody, clone UCHT1, Low Endotoxin



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CNY 8,450.00


货期*
4周

规格
    • 500 ug

Product images

Specifications

Product Data
Clone Name UCHT1
Applications FC, IHC
Recommend Dilution Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 100 µl of whole blood.
Immunohistochemistry on Frozen Sections.
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.
Specificity This antibody recognises a surface protein of peripheral blood T cells of molecular weight 19kD.
As a pan T cell marker this antibody is present on more than 95% of circulating Human peripheral T cells.
Formulation PBS without preservatives
State: Low Endotoxin
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at -20°C.
Avoid repeated freezing and thawing.
Gene Name CD3e molecule
Background T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.
Synonyms T3/Leu-4
Note Endotoxin Level: less than 0.01 EU/µg
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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