CD14 Mouse Monoclonal Antibody [Clone ID: Tük4]

Specifications

Product Data
Clone Name	Tük4
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 106 cells or 100 µl whole blood.
Reactivity	Bovine, Canine, Feline, Goat, Human, Mink, Monkey, Porcine, Rabbit, Sheep, Llama
Host	Mouse
Clonality	Monoclonal
Immunogen	CD14 Human
Specificity	This antibody recognises the CD14 cell surface antigen. CD14 is expressed strongly by most peripheral blood monocytes and weakly on granulocytes. Clone TÜK4 has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner (6). SM1066LE is recommended for this purpose.
Formulation	PBS Label: FITC State: Liquid purified IgG fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	CD14 molecule
Database Link	Entrez Gene 929 Human UniProt ID P08571
Background	CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
Synonyms	CD14
Reference Data

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