CD11b (ITGAM) Mouse Monoclonal Antibody [Clone ID: ICRF44]
CAT#: SM1068PS
CD11b (ITGAM) mouse monoclonal antibody, clone ICRF44, Purified
Size: 200 ug
Need it in bulk or conjugated?
Get a free quote
SM1068PS is a replacement of TA320386.
CNY 4,499.00
货期*
4周
规格
Cited in 1 publication. |
Specifications
Product Data | |
Clone Name | ICRF44 |
Applications | FC, FN, IHC, IP |
Recommend Dilution | Flow Cytometry: Use 10 µl of 1/10-1/100 diluted antibody to label 10e6 cells or 100 µl whole blood. Immunoprecipitation. Immunohistochemistry on Frozen Sections: 1/100-1/1000. The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommend the use of acetone fixation for frozen sections. Recommended Positive Control: Human tonsil. |
Reactivity | Human, Monkey |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Rheumatoid synovial cells and Human mocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line. |
Specificity | This antibody recognizes the CD11b cell surface glycoprotein. This antibody, clone ICRF44 has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release. Negative Species: Cat. |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | integrin subunit alpha M |
Database Link | |
Background | CD11b is a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. |
Synonyms | ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1 |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
---|
Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin
,Sotiriou SN, Orlova VV, Al-Fakhri N, Ihanus E, Economopoulou M, Isermann B, Bdeir K, Nawroth PP, Preissner KT, Gahmberg CG, Koschinsky ML, Chavakis T,
FASEB J.
,PubMed ID 16403785
[ITGAM]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...