CD45 (PTPRC) (CD45RA) Mouse Monoclonal Antibody [Clone ID: MEM-56]

CAT#: SM1115APC

CD45 (PTPRC) (CD45RA) mouse monoclonal antibody, clone MEM-56, APC



Need it in bulk or conjugated?
Get a free quote

CNY 4,340.00


货期*
5周

规格
    • 100 Tests

Product images

Specifications

Product Data
Clone Name MEM-56
Applications FC
Recommend Dilution Flow cytometry (use 20 µl to label 10e cells or 100 µl whole blood).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human thymocytes and T lymphocytes
Specificity The antibody MEM-56 reacts with CD45RA, a 205-220 kDa single chain type I glycoprotein, variant of CD45 (CD45RA isoform). CD45RA is expressed on most of B lymphocytes, resting and native T lymphocytes, medullar thymocytes and monocytes.
Formulation Posphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Label: APC
State: Liquid purified Ig fraction
Label: Conjugated with cross-linked Allophycocyanin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use
Conjugation APC
Storage Condition Store the antibody undiluted at 28°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Should it contain a precipitate we recommend microcentrifugation before use.
Gene Name protein tyrosine phosphatase, receptor type C
Background CD45RA is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on nave T cells and normal plasma cells.
Synonyms PTPRC, Leukocyte common antigen, L-CA, T200
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...