CD49b (ITGA2) Mouse Monoclonal Antibody [Clone ID: AK7]

Specifications

Product Data
Clone Name	AK7
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 10e6 cells or 100 µl whole blood.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Spleen cells from immunised mice were fused with cells of the mouse NSI myeloma cell line.
Specificity	This antibody recognizes the Integrin alpha 2 subunit (CD49b/ITGA2). Clone AK7 Inhibits cell attachment to collagen.
Formulation	PBS, pH 7.4 Label: FITC State: Liquid purified IgG fraction. Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha 2
Database Link	Entrez Gene 3673 Human UniProt ID P17301
Background	CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit (CD29) to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, endothelial cells, monocytes and most adherent cell lines.
Synonyms	Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor
Reference Data

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