CD55 / DAF Mouse Monoclonal Antibody [Clone ID: 67]

Specifications

Product Data
Clone Name	67
Applications	FC
Recommend Dilution	Flow cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	K562 cells
Specificity	This antibody reacts to CD55, also known as DAF.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with distilled water.
Purification	Affinity chromatography on Protein G.
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD55 molecule (Cromer blood group)
Database Link	Entrez Gene 1604 Human UniProt ID P08174
Background	CD55 is the complement regulatory protein, decay accelerating factor (DAF). It is a 70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens. DAF has a wide distribution on cells in non-haemopoietic tissues, particularly epithelium and is specifically found at the foetal-maternal interface in placenta. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.
Synonyms	CR; CROM; DAF; TC
Reference Data

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