CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: FMC46]

CAT#: SM1149R

CD62L (SELL) mouse monoclonal antibody, clone FMC46, PE



Need it in bulk or conjugated?
Get a free quote

CNY 6,369.00


货期*
4周

规格
    • 100 Tests

Product images

Specifications

Product Data
Clone Name FMC46
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of neat antibody to label 106 cells or 100 µl whole blood.
Reactivity Bovine, Human, Monkey, Canine
Host Mouse
Clonality Monoclonal
Immunogen PHA stimulated lymphoblasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity This antibody recognizes CD62L, also known a L-selectin.
Formulation PBS
Label: PE
State: Lyophilized purified IgG
Stabilizer: 5% Sucrose, 1% BSA
Preservative: 0.09% Sodium Azide
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1 ml distilled water.
Purification Affinity chromatography on Protein G
Conjugation PE
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name selectin L
Background CD62L is a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Synonyms SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...