CD55 / DAF Mouse Monoclonal Antibody [Clone ID: BRIC216]

Specifications

Product Data
Clone Name	BRIC216
Applications	FC, IP, WB
Recommend Dilution	Flow Cytometry. Immunoprecipitation. Has been described for previous lots to work in Western blotting under non-reducing conditions.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human fibroblast cell line.
Specificity	This antibody recognises the CD55 antigen. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. CD55 antibody (clone BRIC216) recognises the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF. This antibody has a functional binding affinity to erythrocytes of 8.7 x 10e7 M-1.
Formulation	State: Purified State: Liquid purifed IgG fraction with 0.09% Sodium Azide as preservative.
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD55 molecule (Cromer blood group)
Database Link	Entrez Gene 1604 Human UniProt ID P08174
Background	CD55 antigen is a 70 kD glycoprotein distributed on erythrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. Found specifically at the foetal-maternal interfaces in placenta. CD55 has reduced expression on individuals with paroxysmal noctural haemoglobinuria.
Synonyms	CR; CROM; DAF; TC
Reference Data

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