Cytokeratin 14 (KRT14) Mouse Monoclonal Antibody [Clone ID: LL002]

CAT#: SM1359

Cytokeratin 14 (KRT14) mouse monoclonal antibody, clone LL002, Supernatant



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SM1359 is a replacement of TA327662.SM1359 is a replacement of TA355273.

CNY 5,577.00


货期*
4周

规格
    • 1 ml

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Specifications

Product Data
Clone Name LL002
Applications IHC, WB
Recommend Dilution Western blot.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
Use Polymer anti Mouse/Rabbit IgG as a detection system.
Recommended Positive Control: Skin, tonsil or squamous cell carcinoma.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen A synthetic peptide of 15 amino acid residues from the C-terminus of Human Cytokeratin 14
Specificity LL002 distinguishes stratified epithelial cells from simple epithelial cells and has been reported useful in the identification of squamous cell carcinomas.
Cellular Localization: Cytoplasmic.
Formulation State: Supernatant
State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Gene Name keratin 14
Background Cytokeratin is a type I intermediate filament, expressed by stratifying epithelial cells and can be used to distinguish these cell types from simple epithelial cells, which do not express cytokeratin 14.
Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.
Synonyms Cytokeratin-14, CK14, Keratin 14, K14, KRT14
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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