Cd68 Rat Monoclonal Antibody [Clone ID: FA-11]

CAT#: SM1550FS

Cd68 rat monoclonal antibody, clone FA-11, FITC

Size: 50 ug 100 ug



Need it in bulk or conjugated?
Get a free quote

CNY 3,310.00


货期*
4周

规格
    • 50 ug

Cited in 1 publication.

Product images

Specifications

Product Data
Clone Name FA-11
Applications FC
Recommend Dilution Flow Cytometry: Membrane permeabilisation is required for this application; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Specificity This antibody does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
Formulation PBS, pH 7.4
Label: FITC
State: Liquid purified IgG fraction
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light
Gene Name CD68 antigen
Background The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeablisation.
Synonyms Gp110, Macrosialin, Macrophage marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

Customer Reviews 
Loading...