CD45 Mouse Monoclonal Antibody [Clone ID: CA12.10C12]

CAT#: SM1581

CD45 mouse monoclonal antibody, clone CA12.10C12, Supernatant



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CNY 6,713.00


货期*
4周

规格
    • 2 ml

Cited in 1 publication.

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Specifications

Product Data
Clone Name CA12.10C12
Applications FC, IHC
Recommend Dilution Flow Cytometry.
Immunohistochemistry on frozen sections.
Reactivity Canine
Host Mouse
Clonality Monoclonal
Specificity This antiboyd recognises the homologue of CD45. Clone CA12.10C12 recognises a glycoprotein of approximately 200kD which is expressed by cells of haemapoietic origin.
Formulation containing 0.09% Sodium Azide
State: Supernatant
State: Liquid Tissue Culture Supernatant
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Background CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
Synonyms Leukocyte common antigen, L-CA, PTPRC, T200, LCA
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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