HLAG (HLA-G) Mouse Monoclonal Antibody [Clone ID: MEM-G/1]

Specifications

Product Data
Clone Name	MEM-G/1
Applications	IHC, WB
Recommend Dilution	Western Blot: Reducing reagents are required. Immunohistochemistry on Paraffin Sections: 1/60-1/100. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human placenta- extravillous cytotrophoblast.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Denatured bacterially expressed recombinant Human HLA G heavy chain
Specificity	This antibody reacts with denatured soluble and membrane bound HLA G heavy chain.
Formulation	PBS containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	major histocompatibility complex, class I, G
Database Link	Entrez Gene 3135 Human UniProt ID P17693
Background	The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. HLA G belongs to the HLA class I molecules (HLA Class Ib, nonclassical) and is involved in the presentation of foreign antigens to the immune system. This molecule is expressed on the surface of trophoblast cells and plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.
Synonyms	HLA-6.0, HLAG, MHC class I antigen G
Note	Predicted Molecular Weight: 38 kDa.
Reference Data

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