HLAG (HLA-G) Mouse Monoclonal Antibody [Clone ID: MEM-G/4]

Specifications

Product Data
Clone Name	MEM-G/4
Applications	WB
Recommend Dilution	Western blotting: Recommended dilution: 1-2 μg/ml.  (MWs: HLA-G1 ~45 kDa, HLA-G2 ~45 kDa; HLA-G5 ~28 kDa).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human HLA-G denaturated heavy chain
Specificity	The antibody reacted with denaturated HLA-G heavy chain. The recognized epitope is present only on HLA-G1, -G2 and -G5 molecules. HLA-G1 and -G2 are membrane bound proteins, HLA-G5 is a soluble protein.
Formulation	Phosphate buffered saline pH 7.4 with 15 mM sodium azide as preservative State: Purified State: Liquid
Concentration	lot specific
Purification	Protein A affinity purified immunoglobulin fraction (> 95% by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C for 6 months. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles.
Gene Name	major histocompatibility complex, class I, G
Database Link	Entrez Gene 3135 Human UniProt ID P17693
Background	HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of a heavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternate splicing provides both soluble and membrane bound forms of HLA G, with two soluble isoforms and four membrane bound isoforms. HLA G may be part of the fetal protection system and is expressed on fetal derived placental cells.
Synonyms	HLA-6.0, HLAG, MHC class I antigen G
Reference Data

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