CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: BU15]

Specifications

Product Data
Clone Name	BU15
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/10-1/50 of diluted antibody to label 10e6 cells in 100 µl. Immunoprecipitation. Immunohistochemistry on Frozen Sections: Antibody is reported to be sensitive to formaldehyde fixation and tussue prossesing. Use acetone as fixative. Not suitable for Paraffin Embedded Sections.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises the Integrin alpha X subunit.
Formulation	PBS buffer containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in alqiuots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha X
Database Link	Entrez Gene 3687 Human UniProt ID P20702
Background	CD11c is a 150kD glycoprotein expressed by macrophages, monocytes, granulocytes and NK cells. The antigen is also expressed by hairy cell leukaemia cells. Ligands for CD11c are ICAM-1, iC3b, and fibrinogen. The molecule has a role in mediating adherence of granulocytes and monocytes to endothelium and fibrinogen.
Synonyms	ITGAX, Integrin alpha-X, Leu M5
Reference Data

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