TRAIL (TNFSF10) (95-281) Mouse Monoclonal Antibody [Clone ID: 2E5]

CAT#: SM1847LE

TRAIL (TNFSF10) (95-281) mouse monoclonal antibody, clone 2E5, Low Endotoxin



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CNY 3,810.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 2E5
Applications FC, FN
Recommend Dilution Functional application: High neutralizing activity for human TRAIL in biological assays.
Flow cytometry: 1-10 μg/ml.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant soluble fragment (aa 95-281) of human TRAIL
Specificity This antibody reacts with TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
Formulation Buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized
State: Low Endotoxin
State: Liquid Ig fraction
Concentration lot specific
Purification Protein A (> 95% pure by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name tumor necrosis factor superfamily member 10
Background Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
Synonyms Apo-2 ligand, TNFSF10, APO2L, Apo-2L
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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