LAIR1 Mouse Monoclonal Antibody [Clone ID: NKTA255]

Specifications

Product Data
Clone Name	NKTA255
Applications	FC, IP, WB
Recommend Dilution	Western Blot: This antibody detects a band of approximately 40 kDa. Immunoprecipitation. Flow Cytometry: Use 10 μl of 1/50-1/100 diluted antibody to label 106 cells in 100 μl.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	NK cells lines B12.100 and AM.25. Spleen cells from immunised mice were fused with cells of the P3U1 myeloma cell line.
Specificity	This antibody recognises leukocyte-associated Ig-like receptor-1 (LAIR-1). Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules (See Poggi, A. et al.for details). We recommend the use of Azide Free Antibody Cat.-No SM2048A for this purpose. see Poggi, A. et al. for details.
Formulation	PBS, pH 7.4 State: Aff - Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	leukocyte associated immunoglobulin like receptor 1
Database Link	Entrez Gene 3903 Human UniProt ID Q6GTX8
Background	LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.
Synonyms	LAIR-1, hLAIR1
Reference Data

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