CD163 Mouse Monoclonal Antibody [Clone ID: EDHu-1]

CAT#: SM2160P

CD163 mouse monoclonal antibody, clone EDHu-1, Purified



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CNY 7,538.00


货期*
4周

规格
    • 200 ug

Cited in 1 publication.

Product images

Specifications

Product Data
Clone Name EDHu-1
Applications ELISA, FC, IF, IHC, WB
Recommend Dilution ELISA.
Western Blot.
Immunoassay.
Flow Cytometry.
Immunofluorescence.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections.
Reactivity Human, Monkey, Sheep
Host Mouse
Clonality Monoclonal
Immunogen Leucocytes harvested from pleural cavity of patients with idiopathic spontaneous pneumothorax.
Specificity This antibody recognises the CD163 cell surface antigen.
Clone EDHu-1 is reported to inhibit the binding of haptoglobin:haemoglobin to CD163 (Madsen et al. 2004).
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified IgG fraction from tissue culture supernatant
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD163 molecule
Background CD163 is a 130-140kD glycoprotein expressed by tissue macrophages. CD163 is not expressed by resting peripheral blood leucocytes, but expression may be induced on monocytes by culture in dexamethasone. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone. Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant.
Synonyms M130, Hemoglobin scavenger receptor, Macrophage marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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