CD61 / ITGB3 Hamster Monoclonal Antibody [Clone ID: HM beta 3.1]

CAT#: SM2240R

CD61 / ITGB3 hamster monoclonal antibody, clone HM beta 3.1, PE



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CNY 6,369.00


货期*
4周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name HM beta 3.1
Applications FC
Recommend Dilution Flow Cytometry: Neat-1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Reactivity Mouse, Rat
Host Hamster
Clonality Monoclonal
Immunogen Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
Specificity This antibody recognises the integrin beta 3 subunit (CD61). Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. We recommend the use of SM2240LE for this purpose.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: PE
State: Lyophilized purified IgG fraction.
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1.0 ml distilled water
Concentration lot specific
Purification Affinity Chromatography on Protein G.
Conjugation PE
Storage Condition Store the antibody undiluted at 2-8°C for one month.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name integrin beta 3
Background CD61 is a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.
Synonyms Integrin beta-3, GP3A, GPIIIa
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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