CD61 / ITGB3 Hamster Monoclonal Antibody [Clone ID: HM beta 3.1]
CAT#: SM2240R
CD61 / ITGB3 hamster monoclonal antibody, clone HM beta 3.1, PE
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CNY 6,369.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | HM beta 3.1 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Neat-1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. |
Reactivity | Mouse, Rat |
Host | Hamster |
Clonality | Monoclonal |
Immunogen | Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line. |
Specificity | This antibody recognises the integrin beta 3 subunit (CD61). Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. We recommend the use of SM2240LE for this purpose. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1.0 ml distilled water |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G. |
Conjugation | PE |
Storage Condition | Store the antibody undiluted at 2-8°C for one month. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | integrin beta 3 |
Database Link | |
Background | CD61 is a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. |
Synonyms | Integrin beta-3, GP3A, GPIIIa |
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