CD244 Mouse Monoclonal Antibody [Clone ID: 2B4.69]

Specifications

Product Data
Clone Name	2B4.69
Applications	FC, IP
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/50-1/200 diluted antibody to label 106 cells in 100 µl. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
Specificity	This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD244 molecule
Database Link	Entrez Gene 51744 Human UniProt ID Q9BZW8
Background	The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
Synonyms	NK cell type I receptor protein 2B4, NAIL, NKR2B4
Reference Data

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