Albumin (ALB) Mouse Monoclonal Antibody [Clone ID: AL-01]

Specifications

Product Data
Clone Name	AL-01
Applications	ELISA, IHC, R, WB
Recommend Dilution	ELISA. RIA. Western blotting. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Positive Tissue: Liver.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Fraction of proteins containing Albumin after Ammonium Sulphate precipitation and DEAE-chromatography of Human serum
Specificity	The antibody AL-01 reacts only with Human Serum Albumin, a 65-67 kDa monomeric protein in Human blood plasma; it is produced in liver. No cross-reactivity was observed with other serum proteins.
Formulation	Phosphate buffered saline (PBS), pH~7.4 State: Purified State: Liquid purified Ig fraction (>95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Precipitation Methods
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	69 kDa
Gene Name	albumin
Database Link	Entrez Gene 213 Human UniProt ID P02768
Background	Albumin is a soluble, monomeric protein which comprises about one half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Human serum albumin (65-67 kDa) is the most abundant protein in human blood plasma (produced in the liver). It has a serum half-life of approximately 20 days.
Synonyms	ALB, BSA, HSA, Serum Albumin
Reference Data

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