LFA3 (CD58) Mouse Monoclonal Antibody [Clone ID: MEM-63]
CAT#: SM3032AC
LFA3 (CD58) mouse monoclonal antibody, clone MEM-63, APC
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CNY 4,340.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | MEM-63 |
Applications | FC |
Recommend Dilution | Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Reactivity | Human, Porcine |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | NALM-6 human pre-B cell line |
Specificity | This antibody reacts with CD58 (LFA-3), a 40-70 kDa glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts. |
Formulation | Tris buffered saline (TBS) solution containing 15 mM sodium azide Label: APC State: Liquid purified Ig fraction Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. |
Conjugation | APC |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light. |
Gene Name | CD58 molecule |
Database Link | |
Background | CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B. |
Synonyms | Ag3, LFA-3 |
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