CD63 Mouse Monoclonal Antibody [Clone ID: MEM-259]
CAT#: SM3035F
CD63 mouse monoclonal antibody, clone MEM-259, FITC
Conjugation: Unconjugated Biotin
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CNY 3,810.00
Specifications
Product Data | |
Clone Name | MEM-259 |
Applications | FC, IF |
Recommend Dilution | Flow Cytometry: analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | HPB-ALL T cell line |
Specificity | This antibody reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent. |
Formulation | Phosphate Buffered Saline (PBS) Label: FITC State: Liquid purified Ig fraction Preservative: 15 mM Sodium Azide Label: Fluorescein Isothiocyanate. The reagent is free of unconjugated and adjusted for direct use |
Conjugation | FITC |
Storage Condition | Store the antibody undiluted at 2-8°C. Do Not Freeze! This product is photosensitive and should be protected from light. |
Gene Name | CD63 molecule |
Database Link | |
Background | CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
Synonyms | OMA81H, Granulophysin, Tetraspanin-30, MLA1, TSPAN30, ME491 |
Reference Data |
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