CD98 (SLC3A2) Mouse Monoclonal Antibody [Clone ID: MEM-108]

Specifications

Product Data
Clone Name	MEM-108
Applications	FC
Recommend Dilution	Indirect immunofluorescence analysis by Flow Cytometry: 1:200 as starting dilution.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	RAJI human Burkitt's lymphoma cell line
Specificity	This antibody reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 Label: Biotin State: Liquid purified Ig fraction Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
Gene Name	solute carrier family 3 member 2
Database Link	Entrez Gene 6520 Human UniProt ID P08195
Background	CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with b1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Synonyms	4F2hc, MDU1
Reference Data

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