CD52 Mouse Monoclonal Antibody [Clone ID: HI186]

CAT#: SM3081P

CD52 mouse monoclonal antibody, clone HI186, Purified



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CNY 3,410.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name HI186
Applications FC, IHC
Recommend Dilution Flow Cytometry: 2 µg/ml.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin-Embedded Sections.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human tonsil
Specificity This antibody Clone HI186 reacts with CD52, a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety. Mature CD52 molecule is actually much smaller (approx. 8-9 kDa).
Formulation PBS, pH~7.4
State: Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Protein A Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name CD52 molecule
Background CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
Synonyms HE5, CDw52
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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