CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: MEM-75]

CAT#: SM3104APC

CD71 (TFRC) mouse monoclonal antibody, clone MEM-75, APC



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name MEM-75
Applications FC
Recommend Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen NALM-6 human pre-B cell line
Specificity The antibody MEM-75 reacts with CD71 antigen (transferrin receptor), a 95 kDa type II homodimeric transmembrane glycoprotein expressed on activated B and lymphocytes, macrophages and erythroid precursors; it is lost on resting blood leukocytes.
The antibody MEM-75 does not block binding of transferrin to the receptor.
Formulation PBS containing 15 mM sodium azide as preservative and 0.2% (w/v) high-grade BSA (Protease free) as stabilizer
Label: APC
State: Liquid purified IgG fraction
Label: Conjugated with cross-linked Allophycocyanin under optimum conditions
Purification Size-exclusion chromatography
Conjugation APC
Storage Condition Store the antibody in the dark at 2-8°C.
Do Not Freeze!
Avoid prolonged exposure to light.
Gene Name transferrin receptor
Background CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
Synonyms TfR1, p90, Transferrin receptor protein 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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