CD8A Rat Monoclonal Antibody [Clone ID: YCATE55.9]

CAT#: SM411F

CD8A rat monoclonal antibody, clone YCATE55.9, FITC



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CNY 9,375.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name YCATE55.9
Applications FC
Recommend Dilution Flow Cytometry: Neat - 1/5; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Reactivity Canine
Host Rat
Clonality Monoclonal
Immunogen Canine CD8a chimaeric human IgG1 Fc fusion protein. Spleen cells from immunised DA rat were fused with cells of the Y3/A1.2.3 rat myeloma cell line.
Specificity This antibody, clone YCATE 55.9 was clustered as CD8 in the first canine leukocyte antigen workshop. The antibody reacts with canine CD8a transfectants. Clone YCATE 55.9 is reported to block MHC class I dependant T-cell responses in vitro and in vivo.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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