IL-1B Mouse Monoclonal Antibody [Clone ID: 1D4]

Specifications

Product Data
Clone Name	1D4
Applications	ELISA, FC, IHC
Recommend Dilution	ELISA: 5 µg/ml as coating antibody. Flow Cytometry: 1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl. Immunohistochemistry on Frozen Sections.
Reactivity	Bovine, Goat, Sheep
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant ovine IL-1 Beta
Specificity	This antibody recognises interleukin-1 Beta, and shows no cross-reactivity with IL-6, IL-8, TNF alpha or MCP-1.
Formulation	PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID P21621
Background	Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
Synonyms	IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin
Reference Data

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