CD44 Mouse Monoclonal Antibody [Clone ID: CVS18]

Specifications

Product Data
Clone Name	CVS18
Applications	FC, IHC
Recommend Dilution	Flow cytometry: 1/25 - 1/200, use 10µl of the suggested working dilution to label 106 cells in 100µl. Immunohistochemistry on Frozen sections.
Reactivity	Equine
Host	Mouse
Clonality	Monoclonal
Immunogen	Equine leucocytes
Specificity	Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker.
Formulation	0.09% Sodium azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q05078
Background	CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Synonyms	LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1
Reference Data

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