Integrin alpha 6 (ITGA6) Mouse Monoclonal Antibody [Clone ID: Mab-5A]
CAT#: SM804R
Integrin alpha 6 (ITGA6) mouse monoclonal antibody, clone Mab-5A, PE, Purified
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CNY 6,861.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | Mab-5A |
Applications | FC |
Recommend Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl. |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Rat oesophageal carcinoma cell line B2T. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line. |
Specificity | This CD49f antibody, clone Mab-5A recognizes Rat CD49f, also known as Integrin alpha-6, VLA-6 or CD49 antigen-like family member F. CD49f is a 1130 amino acid ~130 kDa single pass type 1 transmembrane glycoprotein which functions as a receptor for laminin when in association with either beta-1 or beta-4 integrins on platelets and epithelial cells respectively. Clone Mab-5A does not react with Rat fibroblasts. |
Formulation | PBS Label: PE State: Purified State: Lyophilized purified IgG fraction Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide |
Reconstitution Method | Restore with 1.0ml distilled water |
Purification | Affinity Chromatography on Protein G |
Conjugation | PE |
Storage Condition | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | integrin subunit alpha 6 |
Database Link | |
Background | CD49f is a 120 kD integrin family member, also known as VLA-6 alpha chain and alpha6 integrin subunit. CD49f associates with either integrin beta1 (CD29) or integrin beta4 (CD104) to form receptors (VLA-6 or alpha6 beta4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation. |
Synonyms | Integrin alpha-6, VLA-6, VLA6 |
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