GAP43 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Immunoprecipitation. Immunohistochemistry on frozen sections. Western Blot: 1/500 - 1/1000.
Reactivity	Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified rat GAP-43
Specificity	This antibody recognises the protein designated GAP-43.
Formulation	Containing 0.09% Sodium Azide State: Serum State: Liquid serum
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	growth associated protein 43
Database Link	UniProt ID P17677
Background	GAP-43 is a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth. GAP-43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP-43.
Synonyms	Neuromodulin
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.