GPR35 (3rd cytopl. dom.) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 5 - 9 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR35
Specificity	Reacts with G Protein-Coupled Receptor GPR35 (family: GPCR, subfamily: Orphan-A)
Formulation	PBS containing 0.09% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Peptide immunogen affinity column
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	G protein-coupled receptor 35
Database Link	Entrez Gene 2859 Human UniProt ID Q9HC97
Background	GPR35 is an Orphan-A GPCR with an unknown ligand. GPR35 expression was reported only in rat intestine by Northern hybridization; however, another study showed that GPR35 is expressed widely, including pancreatic islets and skeletal muscle, with higher levels in adult lung, small intestine, colon, and stomach. ESTs have been isolated from human fetal lung/testis/B-cell, colon (normal, cancer, and Crohn's disease), breast cancer, pancreatic cancer, and leukemia libraries.
Synonyms	G-protein coupled receptor 35, Kynurenic acid receptor, KYNA receptor
Reference Data

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