SNVsMgp1 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	ELISA: 1 ug/mL
Reactivity	Sin Nombre orthohantavirus
Host	Rabbit
Clonality	Polyclonal
Immunogen	Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Background	Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.
Reference Data

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