SNVsSgp1 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	ELISA: 1 ug/mL
Reactivity	Sin Nombre orthohantavirus
Host	Rabbit
Clonality	Polyclonal
Immunogen	Sin Nombre virus nucleocapsid antibody was raised against a 19 amino acid peptide near the center of the Sin Nombre virus nucleocapsid.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Background	Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice (2). Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA ??anhandle??and is thought to aid in the replication of bunyavirus RNA (3).
Reference Data

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