SAT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry-Paraffin: 1:100, Immunohistochemistry: 1:100, Western Blot: 1:500-1:1000
Reactivity	Human, Mouse, Porcine, Xenopus, Hamster, Cow, Rat, Chicken
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to a C-terminal region within residues 100-171 of the human protein. [Swiss-Prot# P21673]
Formulation	Tris-glycine, 150mM NaCl and 0.05% sodium azide
Purification	peptide affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	spermidine/spermine N1-acetyltransferase 1
Database Link	NP_002961 Entrez Gene 20229 MouseEntrez Gene 302642 RatEntrez Gene 6303 Human UniProt ID P21673
Background	Spermidine/spermine-N1-acetyltransferase (SSAT1) is a short-lived polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Induction of SSAT1 plays an important role in polyamine homoeostasis, since the N1-acetylated polyamines can be excreted or oxidized by acetylpolyamine oxidase.
Synonyms	DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Metabolic pathways

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