H3.3B (H3F3B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, WB
Recommend Dilution	Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Western Blot: 1:500-1:1000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Histone H3.
Formulation	PBS and 0.02% sodium azide
Purification	IgG purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	H3 histone, family 3B (H3.3B)
Database Link	NP_005315 Entrez Gene 15081 MouseEntrez Gene 3021 Human UniProt ID P84243
Background	In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. Histones are believed to be regularly arranged in the deep grove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers.
Synonyms	H3.3B
Reference Data
Protein Pathways	Systemic lupus erythematosus

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