MAT2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, IP, Simple Western, WB
Recommend Dilution	Simple Western, Western Blot: 1.0 ug/ml, Immunocytochemistry/ Immunofluorescence: 1:2000, Immunohistochemistry: 1:200, Immunohistochemistry-Paraffin: 1:200, Immunoprecipitation
Reactivity	Human, Rat, Bovine, Zebrafish, Monkey, Orang-Utan
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide made to an N terminal portion of the human protein (within residues 1-100). [Swiss-Prot# P31153]
Formulation	PBS, 30% glycerol and 0.1% sodium azide
Concentration	lot specific
Purification	peptide affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	methionine adenosyltransferase 2A
Database Link	NP_005902 Entrez Gene 171347 RatEntrez Gene 232087 MouseEntrez Gene 695362 MonkeyEntrez Gene 4144 Human UniProt ID P31153
Background	MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.
Synonyms	MATA2; MATII; SAMS2
Reference Data
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism

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