DRP1 (DNM1L) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, IP
Recommend Dilution	Immunoprecipitation: 1.0 ug/ml, Immunohistochemistry: 2.5 ug/ml, Immunohistochemistry-Paraffin: 2.5 ug/ml, Flow Cytometry: 1:1000
Reactivity	Human, Primate, Mouse, Hamster, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O00429]
Formulation	Tris-glycine, 150mM NaCl and 0.5% sodium azide
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dynamin 1-like
Database Link	NP_036192 Entrez Gene 74006 MouseEntrez Gene 114114 RatEntrez Gene 10059 Human UniProt ID O00429
Background	A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
Synonyms	DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
Reference Data
Protein Pathways	Endocytosis, Fc gamma R-mediated phagocytosis

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