Apolipoprotein E (APOE) Rabbit Polyclonal Antibody
CAT#: TA302010
Rabbit Polyclonal Antibody against APOE (C-term)
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CNY 6,314.00
货期*
5周
规格
经常一起买 (4)
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1:1000, IHC: 1:10~50 |
Reactivity | Human, Monkey, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 36154 Da |
Gene Name | apolipoprotein E |
Database Link | |
Background | Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
Synonyms | AD2; APO-E; LDLCQ5; LPG |
Reference Data | |
Protein Families | Adult stem cells, Druggable Genome, Secreted Protein, Stem cell - Pluripotency |
Protein Pathways | Alzheimer's disease |
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