PARP6 Rabbit Polyclonal Antibody

CAT#: TA302166

Rabbit Polyclonal Antibody against PARP6 (C-term)



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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经常一起买 (2)
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:1000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-583 amino acids from the C-terminal region of human Parp6.
Formulation Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 71115 Da
Gene Name poly(ADP-ribose) polymerase family member 6
Background Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
Synonyms ARTD17; PARP-6-B1; PARP-6-C; pART17
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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