ACTR1A Goat Polyclonal Antibody

Specifications

Product Data
Applications	FC, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:1,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Dog, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-YEEDGARSIHRKT, from the C Terminus of the protein sequence according to NP_005727.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46240 Da
Gene Name	ARP1 actin-related protein 1 homolog A, centractin alpha
Database Link	NP_005727 Entrez Gene 54130 MouseEntrez Gene 403791 DogEntrez Gene 10121 Human UniProt ID P61163
Background	This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq]
Synonyms	ARP1; Arp1A; CTRN1
Reference Data

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